diff --git a/applications/message_process/CMakeLists.txt b/applications/message_process/CMakeLists.txt
index 51d514b..9c80672 100644
--- a/applications/message_process/CMakeLists.txt
+++ b/applications/message_process/CMakeLists.txt
@@ -18,4 +18,4 @@
 
 add_library(message_process STATIC src/message_process.cc)
 target_include_directories(message_process PUBLIC include ${LINUX_DRIVER_STACK_PATH}/kernel)
-target_link_libraries(message_process PRIVATE cmsis_core inference_process)
+target_link_libraries(message_process PRIVATE cmsis_core inference_process mailbox)
diff --git a/applications/message_process/include/message_process.hpp b/applications/message_process/include/message_process.hpp
index e820b60..b3c1bdd 100644
--- a/applications/message_process/include/message_process.hpp
+++ b/applications/message_process/include/message_process.hpp
@@ -21,6 +21,7 @@
 
 #include <ethosu_core_interface.h>
 #include <inference_process.hpp>
+#include <mailbox.hpp>
 
 #include <cstddef>
 #include <cstdio>
@@ -82,10 +83,12 @@
 
 class MessageProcess {
 public:
-    MessageProcess(ethosu_core_queue &in, ethosu_core_queue &out, InferenceProcess::InferenceProcess &inferenceProcess);
+    MessageProcess(ethosu_core_queue &in,
+                   ethosu_core_queue &out,
+                   Mailbox::Mailbox &mbox,
+                   InferenceProcess::InferenceProcess &inferenceProcess);
 
     void run();
-    void handleIrq();
     bool handleMessage();
     void sendPong();
     void sendInferenceRsp(uint64_t userArg, std::vector<InferenceProcess::DataPtr> &ofm, bool failed);
@@ -93,7 +96,10 @@
 private:
     QueueImpl queueIn;
     QueueImpl queueOut;
+    Mailbox::Mailbox &mailbox;
     InferenceProcess::InferenceProcess &inferenceProcess;
+    void handleIrq();
+    static void mailboxCallback(void *userArg);
 };
 
 } // namespace MessageProcess
diff --git a/applications/message_process/src/message_process.cc b/applications/message_process/src/message_process.cc
index 4333640..4533455 100644
--- a/applications/message_process/src/message_process.cc
+++ b/applications/message_process/src/message_process.cc
@@ -100,10 +100,6 @@
     SCB_CleanDCache();
 #endif
 
-    // TODO replace with mailbox driver APIs
-    volatile uint32_t *set = reinterpret_cast<volatile uint32_t *>(0x41A00014);
-    *set                   = 0x1;
-
     return true;
 }
 
@@ -132,9 +128,12 @@
 
 MessageProcess::MessageProcess(ethosu_core_queue &in,
                                ethosu_core_queue &out,
+                               Mailbox::Mailbox &mbox,
                                ::InferenceProcess::InferenceProcess &_inferenceProcess) :
     queueIn(in),
-    queueOut(out), inferenceProcess(_inferenceProcess) {}
+    queueOut(out), mailbox(mbox), inferenceProcess(_inferenceProcess) {
+    mailbox.registerCallback(mailboxCallback, reinterpret_cast<void *>(this));
+}
 
 void MessageProcess::run() {
     while (true) {
@@ -238,6 +237,7 @@
     if (!queueOut.write(ETHOSU_CORE_MSG_PONG)) {
         printf("Failed to write pong.\n");
     }
+    mailbox.sendMessage();
 }
 
 void MessageProcess::sendInferenceRsp(uint64_t userArg, vector<DataPtr> &ofm, bool failed) {
@@ -259,5 +259,12 @@
     if (!queueOut.write(ETHOSU_CORE_MSG_INFERENCE_RSP, rsp)) {
         printf("Failed to write inference.\n");
     }
+    mailbox.sendMessage();
 }
+
+void MessageProcess::mailboxCallback(void *userArg) {
+    MessageProcess *_this = reinterpret_cast<MessageProcess *>(userArg);
+    _this->handleIrq();
+}
+
 } // namespace MessageProcess